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RESISTANCE, APC
Descriptors Found:
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DeCS
Descriptor
English
:
Activated Protein C Resistance
Descriptor
Spanish
:
Resistencia a la Proteína C Activada
Descriptor
Portuguese
:
Resistência à Proteína C Ativada
Synonyms
English
:
APC Resistance
Resistance, APC
Tree Number:
C15.378.100.100.037
C15.378.100.141.036
C15.378.925.050
C16.320.099.037
Definition
English
:
A hemostatic disorder characterized by a poor anticoagulant response to activated
protein C
(APC). The activated form of
Factor V
(
Factor Va
) is more slowly degraded by activated
protein C
.
Factor V
Leiden
mutation
(R506Q) is the most common cause of APC resistance.
See Related
English
:
Protein C Deficiency
History Note
English
:
99
Allowable Qualifiers
English
:
BL
blood
CF
cerebrospinal fluid
CI
chemically induced
CL
classification
CO
complications
CN
congenital
DI
diagnosis
DG
diagnostic imaging
DH
diet therapy
DT
drug therapy
EC
economics
EM
embryology
EN
enzymology
EP
epidemiology
EH
ethnology
ET
etiology
GE
genetics
HI
history
IM
immunology
ME
metabolism
MI
microbiology
MO
mortality
NU
nursing
PS
parasitology
PA
pathology
PP
physiopathology
PC
prevention & control
PX
psychology
RT
radiotherapy
RH
rehabilitation
SU
surgery
TH
therapy
UR
urine
VE
veterinary
VI
virology
Record Number:
33772
Unique Identifier:
D020016
Occurrence in VHL
:
Similar:
DeCS